Table 2.
Associations Between TSH and Thyroid Hormone Concentrations and Parameters of Diastolic Left Ventricular Function
| |
E (mm/s) |
A (mm/s) |
e′ (mm/s) |
a′ (mm/s) |
||||
|---|---|---|---|---|---|---|---|---|
| β | p | β | p | β | p | β | p | |
| TSH (mU/L) | ||||||||
| Sex-adjusted | −0.02 | 0.5 | 0.007 | 0.8 | −0.05 | 0.01 | 0.008 | 0.7 |
| Model 1 | −0.02 | 0.4 | 0.001 | 0.9 | −0.05 | 0.006 | −0.001 | 0.9 |
| Model 2 | −0.02 | 0.3 | −0.02 | 0.2 | −0.04 | 0.03 | −0.02 | 0.4 |
| Model 3 | −0.03 | 0.2 | −0.02 | 0.2 | −0.05 | 0.009 | −0.02 | 0.4 |
| FT4 (ng/dL) | ||||||||
| Sex-adjusted | −0.02 | 0.4 | 0.005 | 0.8 | 0.04 | 0.06 | 0.03 | 0.2 |
| Model 1 | −0.04 | 0.06 | 0.05 | 0.01 | −0.008 | 0.6 | 0.07 | 0.002 |
| Model 2 | −0.03 | 0.1 | 0.04 | 0.03 | −0.006 | 0.8 | 0.06 | 0.004 |
| Model 3 | −0.04 | 0.09 | 0.04 | 0.03 | −0.01 | 0.6 | 0.06 | 0.005 |
| FT3 (pg/mL) | ||||||||
| Sex-adjusted | 0.02 | 0.4 | 0.06 | 0.01 | 0.02 | 0.5 | 0.05 | 0.05 |
| Model 1 | −0.03 | 0.2 | 0.08 | <0.0001 | −0.04 | 0.06 | 0.08 | <0.0001 |
| Model 2 | −0.02 | 0.5 | 0.01 | 0.6 | −0.02 | 0.4 | 0.02 | 0.4 |
| Model 3 | −0.01 | 0.5 | 0.009 | 0.7 | −0.2 | 0.4 | 0.02 | 0.4 |
| TT3 (ng/dL) | ||||||||
| Sex-adjusted | 0.07 | <0.0001 | 0.11 | <0.0001 | 0.06 | 0.009 | 0.05 | 0.02 |
| Model 1 | 0.04 | 0.04 | 0.10 | <0.0001 | 0.04 | 0.03 | 0.06 | 0.007 |
| Model 2 | 0.07 | 0.001 | 0.02 | 0.2 | 0.07 | <0.0001 | 0.007 | 0.7 |
| Model 3 | 0.07 | 0.001 | 0.02 | 0.2 | 0.06 | 0.001 | 0.008 | 0.7 |
Results from linear regression analysis according to several models: a sex-adjusted model; a model with additional adjustment for age, height, weight, and active smoking; a model with additional adjustment for systolic blood pressure and heart rate; and a model with additional adjustment for LVEDD and relative wall thickness. Parameters of diastolic function (E, A, e′, and a′) were used as dependent variables; TSH, FT4, FT3 and TT3 were independent variables.