Table 2.
Differentially Expressed Genes of hPDLCs Under Cyclic Tensile Stress (Partial Microarray Data)
| Name | Description | p-Value | Fold change | Gene ID |
|---|---|---|---|---|
| Up-regulated genes | ||||
| Response to stimulus | ||||
| APOE | apolipoprotein E | 0.017483 | 3.102327 | 348 |
| SPP1 | secreted phosphoprotein 1 | 0.003096 | 9.22774 | 6696 |
| TAC1 | tachykinin, precursor 1 | 0.023223 | 1.854219 | 6863 |
| THBD | thrombomodulin | 0.017664 | 2.075896 | 7056 |
| CMA1 | chymase 1, mast cell | 0.021977 | 1.60568 | 1215 |
| SFRP2 | secreted frizzled-related protein 2 | 0.022874 | 1.508726 | 6423 |
| LAT2 | linker for activation of T cells family | 0.026814 | 1.767791 | 7462 |
| TPD52L1 | tumor protein D52-like 1 | 0.03251 | 2.121754 | 7164 |
| ASCL2 | achaete-scute complex-like 2 | 0.022832 | 1.926807 | 430 |
| ADRA2A | adrenergic, alpha-2A-, receptor | 0.009503 | 1.896106 | 150 |
| Neg. regulation of cell proliferation | ||||
| DPT | dermatopontin | 0.036332 | 1.579927 | 1805 |
| ASCL2 | achaete-scute complex-like 2 | 0.022832 | 1.926807 | 430 |
| APOE | apolipoprotein E | 0.017483 | 3.102327 | 348 |
| BTG1 | B-cell translocation gene 1 | 0.031139 | 1.523646 | 694 |
| NPPA | natriuretic peptide precursor A | 0.041759 | 2.024056 | 4878 |
| SPP1 | secreted phosphoprotein 1 | 0.003096 | 9.22774 | 6696 |
| Cell adhesion | ||||
| BCL2L11 | BCL2-like 11 | 0.027295 | 1.926735 | 10018 |
| DLL1 | delta-like 1 | 0.022419 | 1.541046 | 28514 |
| SFRP2 | secreted frizzled-related protein 2 | 0.022874 | 1.508726 | 6423 |
| PRPH | Peripherin | 0.047233 | 1.590701 | 5630 |
| SPP1 | secreted phosphoprotein 1 | 0.003096 | 9.22774 | 6696 |
| Cell growth | ||||
| CISH | cytokine-inducible SH2-containing protein | 0.0326 | 1.614761 | 1154 |
| SFRP2 | secreted frizzled-related protein 2 | 0.022874 | 1.508726 | 6423 |
| NPPA | natriuretic peptide precursor A | 0.041759 | 2.024056 | 4878 |
| BTG1 | B-cell translocation gene 1 | 0.031139 | 1.523646 | 694 |
| APOE | apolipoprotein E | 0.017483 | 3.102327 | 348 |
| SPP1 | secreted phosphoprotein 1 | 0.003096 | 9.22774 | 6696 |
| Down-regulated genes | ||||
| SEMA3C | sema domain, immunoglobulin domain (Ig) | 3.03E-04 | 2.899486 | 10512 |
| SYNJ1 | synaptojanin 1 | 0.008957 | 2.348813 | 8867 |
| SLC8A1 | solute carrier family 8, member 1 | 0.019753 | 2.31181 | 6564 |
| GLOXD1 | glyoxalase domain containing 1 | 0.017959 | 2.308117 | 84842 |
| CENTB2 | centaurin, beta 2 | 0.028033 | 2.293343 | 23527 |
| SAC | testicular soluble adenylyl cyclase | 0.008068 | 2.258588 | 55811 |
| WDR51B | WD repeat domain 51B | 0.0117322 | 2.127292 | 282809 |
hPDLC, human periodontal ligament cells; Neg., negative.