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A) MMP-12 and a cluster of chemokines (CXCL8, CXCL5, and CXCL1) exhibited the highest fold changes in real-time PCR validation of microarray analysis. B) MMP-12, CXCL8, CXCL5, and CXCL1 expression was specifically up-regulated by tropoelastin signaling. Dotted line represents a fold change of 1. Results shown are averages of 3 independent experiments. **P < 0.01; ***P < 0.001.
