TABLE 2.

Effects of cellular respiratory inhibitors on the candidacidal activity of lactoferrin^a

Incubation	Inhibitor (concn)	Cell viability (% of control)b
Aerobic		15 ± 2
Aerobic	Azide (5 mM)	96 ± 4
Aerobic	CCCP (500 μM)	94 ± 3
Aerobic	DNP (10 μM)	47 ± 4
Aerobic	Antimycin (10 μM)	92 ± 5
Anaerobicc		81 ± 4
Anaerobicd		92 ± 3

^aC. albicans cells were incubated with or without the respiratory inhibitors and were then treated with lactoferrin for 2 h.

^bValues are the means ± standard deviations from duplicates of at least three independent experiments.

^cAssays were performed under anaerobic conditions (80% N₂, 10% CO₂, 10% H₂).

^dAssays were performed in the presence of 2.5 mM l-cysteine.