Table 2.
Diet | n | Initial BW (g) | BW after WD (g) | Final BW, age 31 wk (g) | Final fat mass (% BW) | Final lean mass (%BW) | Food consumption (g/mouse/d) |
---|---|---|---|---|---|---|---|
Chow | 9 | 17.5 ± 0.8 | 25.0 ± 2.5 | 27.1 ± 2.4 | 22.6 ± 1.5 | 77.4 ± 1.5 | 2.5 ± 0.3 |
HDCA | 14 | 18.1 ± 1.1 | 25.2 ± 2.5 | 24.2 ± 1.5** | 19.1 ± 0.8* | 80.9 ± 0.8* | 2.3 ± 0.3 |
Values are means ± sd of each group. Initial body weight (BW) was measured at 8 wk of age. BW after Western diet (WD) was measured at 16 wk of age after the mice were placed on a WD for 8 wk. Final BW and composition (fat mass and lean mass percentages) were measured at euthanasia, at 31 wk of age, after the mice received 8 wk of WD, followed by 15 wk feeding of chow diet or chow diet + 1.25% HDCA (HDCA). Average food consumption data were obtained from wk 2 to 14 during the period of chow diet or HDCA diet feeding.
P = 0.05,
P = 0.01 vs. chow.