Figure 5.
Effect of McTnT deletion mutants on the rate of tension redevelopment in TmWT and TmH276N fibers. Rate of tension development ktr was measured as described previously (31). A) Two-way ANOVA revealed a significant interaction effect (P<0. 01), indicating that the differences between the effects of McTnT1–44Δ and McTnT45–74Δ on ktr were dissimilar against TmWT and TmH276N backgrounds. B) Post hoc multiple pairwise comparisons revealed that McTnT1–44Δ significantly decreased ktr (by ∼17%), only in TmH276N fibers. At least 7 determinations were done for each group. Values are reported as mean ± sem. *P < 0.05.