Table 2.
Results of meta-analysis
| Outcome | No. of study |
Sample size |
Heterogeneity (P, I2) | Overall effect size | 95%CI of overall effect | P value | |
| LATG | OTG | ||||||
| Operating time (min) | 9 | 436 | 785 | < 0.001, 94% | WMD = 57.68 | 30.48-84.88 | < 0.001 |
| Blood loss | 7 | 309 | 404 | < 0.001, 95% | SMD = -1.71 | -2.48 - -0.94 | < 0.001 |
| Retrieved lymph nodes | 9 | 436 | 785 | 0.09, 41% | WMD = -1.41 | -3.15 - 0.32 | 0.11 |
| Proximal margin (cm) | 2 | 163 | 475 | 1.00, 0% | WMD = -0.40 | -0.82 - 0.02 | 0.06 |
| Distal margin (cm) | 2 | 163 | 475 | 0.67, 0% | WMD = 0.46 | -0.40 - 1.32 | 0.29 |
| Analgesics given | 4 | 221 | 300 | < 0.001, 93% | SMD = -0.86 | -1.62 - -0.11 | 0.02 |
| Duration of fever (d) | 2 | 112 | 138 | 0.47, 0% | WMD = -1.58 | -1.80 - -1.37 | < 0.001 |
| Time to first flatus (d) | 7 | 316 | 419 | < 0.001, 91% | WMD = -0.76 | -1.22 - -0.30 | 0.001 |
| Time to oral intake (d) | 4 | 161 | 257 | 0.04, 63% | WMD = -0.81 | -1.26 - -0.35 | < 0.001 |
| Hospital stay (d) | 8 | 354 | 691 | 0.02, 56% | WMD = -2.67 | -3.96 - -1.38 | < 0.001 |
| Overall complications | 9 | 436 | 785 | 0.10, 40% | RR = 0.79 | 0.61-1.02 | 0.07 |
| Surgical complications | 9 | 436 | 785 | 0.42, 2% | RR = 0.83 | 0.64-1.08 | 0.16 |
| Medical complications | 7 | 343 | 614 | 0.70, 0% | RR = 0.41 | 0.19-0.90 | 0.03 |
| Mortality | 4 | 229 | 490 | 0.66, 0% | RR = 0.72 | 0.20-2.57 | 0.61 |
WMD: Weighted mean difference; SMD: Standard mean difference; LATG: Laparoscopy-assisted total gastrectomy; OTG: Open total gastrectomy.