Table 1.

Criteria for the pre-selection of patients.

Inclusion Criteria	Exclusion Criteria
25 to 55 years of age	Habits or occupations that lead to sleep deprivation or alterations in the sleep-wake cycle
Sedentary	History of regular sports activities
Body mass index≤30 kg/m2	Inability to perform physical exercise
AHI>10/h	Other sleep disorders
Hemogram, cholesterol, HDL, triglycerides, fasting glucose, creatinine, TSH within the normal range	Anatomical obstructive upper airway: tonsils grade III and IV and septal deviation grade III (severe) that can affect the outcome of CPAP use
Lung function test (spirometry), chest X-rays (for smokers and former smokers), resting and stress electrocardiogram and otorhinolaryngologic examination without significant changes	Clinical disease decompensation (chronic obstructive pulmonary disease, asthma, interstitial lung diseases, neuromuscular diseases, heart failure, thyroid disease, rheumatologic and psychiatric diseases)
	Use of sleeping pills
	Other treatments for OSAS
	Loss of dental support that subsequently compromises the retention of OA
	Periodontal disease
	Dental crown/tooth root relationship less than or equal to 1
	Primary dental care (cavities, root canal treatment or retreatment or extensive dental prostheses)
	Anterior open bite
	Protrusive displacement less than 5 mm
	Limited mouth opening
	Alcoholism

AHI: apnea-hypopnea index; HDL: high-density-lipoprotein; TSH: thyreoid stimulant hormone.