Table 2.

Diffusion tensor imaging indices and volumetric results in the corpus callosum segments in the relapsing-remitting multiple sclerosis and healthy control groups.

		CC1	CC2	CC3	CC4	CC5	CC total
AD (10-3 mm2/s)	RRMS	1.69±0.1	1.56±0.2	1.54±0.1	1.59±0.1	1.77±0.1	1.66±0.1
	HC	1.65±0.1	1.50±0.1	1.48±0.1	1.55±0.1	1.71±0.1	1.61±0.1
	p-value	0.12	0.06	0.02**	0.23	0.01*	0.007*
RD (10-3 mm2/s)	RRMS	0.48±0.1	0.51±0.1	0.46±0.1	0.50±0.1	0.45±0.1	0.48±0.1
	HC	0.42±0.1	0.44±0.04	0.41±0.04	0.44±0.04	0.37±0.04	0.42±0.03
	p-value	<0.001*	<0.001*	0.003*	<0.001*	<0.001*	<0.001*
FA	RRMS	0.67±0.1	0.62±0.1	0.65±0.1	0.63±0.1	0.71±0.04	0.66±0.04
	HC	0.71±0.0	0.66±0.03	0.67±0.04	0.67±0.04	0.75±0.03	0.70±0.02
	p-value	0.001*	0.003*	0.08	0.006*	<0.001*	<0.001*
MD (10-3 mm2/s)	RRMS	0.88±0.1	0.86±0.1	0.82±0.1	0.87±0.1	0.89±0.1	0.88±0.1
	HC	0.83±0.1	0.79±0.1	0.77±0.1	0.81±0.1	0.82±0.04	0.81±0.03
	p-value	0.002*	0.002*	<0.001*	0.003*	<0.001*	<0.001*

Mann-Whitney non-parametric test. The group results are expressed as the mean ± standard deviation (SD). * Significant differences between groups; ** trends;

AD: axial diffusivity; CC: corpus callosum; CC1: genu; CC2: anterior midbody; CC3: posterior midbody; CC4: isthmus; CC5: splenium; CC total: corpus callosum total; FA: fractional anisotropy; HC: healthy control group; MD: mean diffusivity;

RD: radial diffusivity; RRMS: relapsing-remitting multiple sclerosis.