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. Author manuscript; available in PMC: 2013 Aug 27.
Published in final edited form as: Anesthesiology. 2011 Nov;115(5):1012–1021. doi: 10.1097/ALN.0b013e31823306cf

Table 1.

Respiratory Mechanics

Peak Inspiratory Pressure (cm H2O)
Respiratory Compliance (μl/cm H2O)
1 h HVT End of HVT 1 h HVT End of HVT
Inhalation
 0 ppm H2S 35 ± 0.3 43 ± 0.1* 38 ± 1.1 22 ± 1.6
 1 ppm H2S 34 ± 0.4 42 ± 0.7* 40 ± 1.3 20 ± 2.2*
 5 ppm H2S 35 ± 0.6 42 ± 0.1* 40 ± 0.6 18 ± 1.3*
 60 ppm H2S 33 ± 0.5 42 ± 0.2* 39 ± 0.9 18 ± 0.7*
Intravascular infusion
 Vehicle 34 ± 0.2 43 ± 0.3* 40 ± 0.4 24 ± 1.4*
 Na2S, 0.55 mg/kg 35 ± 0.2 39 ± 0.6 39 ± 0.6 34 ± 2.3

Respiratory mechanics were measured in mice subjected to high tidal volume (HVT) ventilation. Values represent mean ± SEM after 60 min (1 h HVT) and at the end of HVT ventilation (maximum 240 min).

*

P < 0.05 vs. 1 h HVT.

P < 0.05 vs. vehicle.

H2S = hydrogen sulfide; Na2S = sodium sulfide.