Table 3.
Cross-species identification of GRE half-sites in 5’-regulatory regions of corticosteroid-enhanced genes
| Gene Name | Species | Position | Sequence |
|---|---|---|---|
| Insulin-like growth factor-binding protein-1 (IGFBP1) | Rat | −356 | TGGTCTAATCTGTTCTTgCTTTtcct |
| (6, 6) | Mouse | −315 | TGGTCTAATCTGTTCTTtCTTTagtc |
| Solute carrier family 19, member 1 | Rat | −8139 | AGgCCCGTctTGTTCTTTCTCTTCCg |
| (6, 2) | Mouse | −8313 | AGtCCCGTgcTGTTCTTTCTCTTCCt |
| Rat | −8099 | cagatTCAAGTGTTCTCAAGTGAGCC | |
| Mouse | −8274 | gcagcTCAAGTGTTCTCAAGTGAGCC | |
| Solute carrier family 29, member 2 | Rat | −8252 | AtTTTGGATGTGTTCTAACCTCAgCA |
| (6, 3) | Mouse | −6778 | AgTTTGGATGTGTTCTAACCTCAaCA |
| Calcitonin; receptor activity modifying protein 3 | Rat | −2761 | CCaagccTgCTGTTCTGCCAGGACAA |
| (3, 1) | Mouse | −2527 | CCtcaggTcCTGTTCTGCCAGGACAA |
| Cathepsin S | Rat | −3800 | CagattgAaATGTTCTgTTTCAaCAT |
| (3, 6) | Mouse | −1027 | CctggccAgATGTTCTaTTTCAgCAT |
| Rat | −8469 | CAGGGAAGTCTGTTCTGttgaGtaaA | |
| Mouse | −4642 | CAGGGAAGTCTGTTCTGcattGaggA | |
| Complement component 1, q subcomponent β | Rat | −9034 | caGGGTCTaTTGTTCTGTtTTGGTCA |
| (5, 5) | Mouse | −9282 | agGGGTCTgTTGTTCTGTgTTGGTCA |
| Interferon-γ receptor | Rat | −1793 | AActgTGTCCTGTTCTaGCTTGTATT |
| (5, 8) | Mouse | −1754 | AAtcaTGTCCTGTTCTgGCTTGTATT |
| Aspartoacylase | Rat | −9804 | CAGTATTCTATGTTCTGAGAAAGAAA |
| (3, 4) | Mouse | −9062 | CAGTATTCTATGTTCTGAGAAAGAAA |
| Rat | −3324 | acCCcaGCTCTGTTCTGGTTATCGTT | |
| Mouse | −3194 | taCCtgGCTCTGTTCTGGTTATCGTT | |
| Nuclear distribution gene C | Rat | −432 | TTTGTAAAgCTGTTCTAtaCAAACTA |
| (4, 2) | Mouse | −388 | TTTGTAAAaCTGTTCTActCAAACTA |
| Aspartate aminotransferase cytosolic | Rat | −1792 | AATATTTATTTGTTCTTAGCCAAACt |
| (10, 2) | Mouse | −1771 | AATATTTATTTGTTCTTAGCCAAACc |
| Lysyl oxidase | Rat | −199 | TGTTCCGTTTTGTTCTTTCCCCTTAA |
| (9, 1) | Mouse | −213 | TGTTCCGTTTTGTTCTTTCCCCTTAA |
| Kruppel-like factor 15 | Rat | −3174 | TGACAAGCCATGTTCTACTGCAcAGt |
| (2, 3) | Mouse | −8369 | TGACAAGCCATGTTCTACTGCAtAGa |
| HIF-1 responsive RTP801 | Rat | −1164 | GGCCCTGCAGTGTTCTGTCCCtaagg |
| (6, 9) | Mouse | −906 | GGCCCTGCAGTGTTCTGTCCCcctaa |
| Rat | −1844 | AAGACCTGGCTGTTCTAAAAaTCAGG | |
| Mouse | −1608 | AAGACCTGGCTGTTCTAAAAgTCAGG | |
| Rat | −6010 | GGGTGCACcCTGTTCTcTAGCCGCCt | |
| Mouse | −6086 | GGGTGCACtCTGTTCTtTAGCCGCCc | |
| Connective tissue growth factor | Rat | −3424 | gGGGtaAaAATGTTCTCTTGAAGTCA |
| (6, 6) | Mouse | −3184 | tGGGgtAgAATGTTCTCTTGAAGTCA |
| Vimentin (VIM) | Rat | −5475 | CCACCTAAgTTGTTCTGCtTtGAATA |
| (19, 8) | Mouse | −4962 | CCACCTAAATTGTTCTGCcTaGAATA |
| Osteonectin; secreted acidic cystein-rich glycoprotein | Rat | −300 | AGGCCTGtcCTGTTCTAGGTGATTCC |
| (3, 5) | Mouse | −291 | AGGCCTGgCCTGTTCTAGGTGATTCC |
| Rat | −8667 | tcGgtTtcaCTGTTCTGGAATCaTAG | |
| Mouse | −8405 | agGccTggcCTGTTCTGGAATCtTAG | |
| ADP-ribosylation-like 4 | Rat | −1975 | ACCCTCCAGATGTTCTCtAGGgCACC |
| (6, 6) | Mouse | −2831 | ACCCTCCAGATGTTCTCcAGGaCACC |
| Regulator of G protein signaling 2 | Rat | −8277 | AGtATAAAACTGTTCTTATTTGATcg |
| (3, 2) | Mouse | −7555 | AGcATAAAACTGTTCTTATTTGATgt |
| Lipocalin 7; glucocorticoid-inducible protein | Mouse | −2553 | tacCCAGGtCTGTTCTGTTaAAGCCt |
| (6, 6) | Human | −1502 | gtaCCAGGcCTGTTCTGTTgAAGCCa |
| Serum/glucocorticoid regulated kinase | Mouse | −972 | AaGaACAgAATGTTCTCgGAGATTAg |
| (10, 6) | Human | −1164 | AcGgACAaAATGTTCTCaGAGATTAc |
| Mouse | −1034 | CCTCCTCACGTGTTCTTGGCATGGCt | |
| Human | −1226 | CCTCCTCACGTGTTCTTGGCATGGCa |
Numbers in parentheses under Gene Name indicate numbers of GRE half-sites identified in rat and mouse respectively. Sequence column presents regions containing half-sites with conservation in flanking regions. GRE half-sites are underlined, and nonconserved nucleotides are presented in lowercase letters.