Table 4.
Cross-species identification of GRE half-sites in 5’-regulatory regions of downregulated genes
| Gene Name | Species | Position | Sequence |
|---|---|---|---|
| Urinary plasminogen activator; urokinase (uPA) | Rat | −3158 | ATCTgAGAtgTGTTCTTTGCCcCCcA |
| (5, 6) | Mouse | −2608 | ATCTaAGAccTGTTCTTTGCCtCCaA |
| Rat | −3248 | TcCTgTTCTCTGTTCTGCATTCACTG | |
| Mouse | −2698 | TaCTtTTCTCTGTTCTGCATTCACTG | |
| Rat | −5592 | CCATACTGAATGTTCTTAGTATAGCA | |
| Mouse | −4620 | CCATACTGAATGTTCTTAGTATAGCA | |
| n-acetyltransferase; Camello 4 (Cml4) | Rat | −7848 | ACAtTgAAAGTGTTCTTCAGAGgCCA |
| (5, 10) | Mouse | −7258 | ACAcTtAAAGTGTTCTTCAGAGaCCA |
| 17β-Hydroxysteroid dehydrogenase type 2 (HSD17β2) | Rat | −4817 | gaAAGGCACaTGTTCTCAGCAACgTT |
| (7, 6) | Mouse | −4877 | agAAGGCACgTGTTCTCAGCAACaTT |
| Ferroportin 1; iron exporter (Slc39a1) | Rat | −1064 | aGctCCCACCTGTTCTTAcCcCTCag |
| (6, 4) | Mouse | −1661 | gGacCCCACCTGTTCTTAgCaCTCtc |
| Monocarboxylic acid transporter (Slc16a1) | Rat | −4034 | cGTAAGATTATGTTCTCTTTcTAAAA |
| (6, 8) | Mouse | −4120 | tGTAAGATTATGTTCTCTTTtTAAAA |
| Rat | −9123 | TGAGACCATGTGTTCTAAGACAcCAA | |
| Mouse | −8740 | TGAGACCATGTGTTCTAAGACAtCAA | |
| Plasmolipin | Rat | −3656 | gCctCccTCTTGTTCTTTGTTTTTTG |
| (6, 3) | Mouse | −2900 | cCtcCtgTCTTGTTCTTTGTTTTTTG |
| Rat | −3968 | AgCCCcGCTTTGTTCTGAGCTTGGaC | |
| Mouse | −3128 | AcCCCaGCTTTGTTCTGAGCTTGGtC | |
| Angiopoietin-like 2 (Angptl2) | Rat | −1825 | AtTAACtACCTGTTCTtTGGCtaTtG |
| (4, 8) | Mouse | −1848 | AgTAACcACCTGTTCTcTGGCctTgG |
| Rat | −2194 | ACCAcATAgCTGTTCTTGCCCCtGTc | |
| Mouse | −2224 | ACCAtATAaCTGTTCTTGCCCCaGTg | |
| Kynurenine 3-hydroxylase (Kmo) | Rat | −1043 | ccttCcagTGTGTTCTCATCAGAAAT |
| (4, 4) | Mouse | −819 | atgcCattTGTGTTCTCATCAGAAAT |
| Rat | −2948 | cTTTGCACTCTGTTCTTTAtGGGATG | |
| Mouse | −2867 | aTTTGCACTCTGTTCTTTAgGGGATG | |
| Rat | −3001 | GgACCTGCTTTGTTCTTGTTGATGCC | |
| Mouse | −2918 | GaACCTGCTTTGTTCTTGTTGATGCC | |
| Glucocorticoid receptor (GCR) | NM | ||
| Calcium-dependent, elastin-binding protein (Fbln5) | NM | ||
| Insulin-like growth factor 2 receptor (IGF2R) | NM | ||
| Uterine sensitization-associated gene-1 (Usag1) | NM | ||
| Pyruvate dehydrogenase phosphatase isoenzyme 2 (PDP2) | NM | ||
| Potassium inwardly-rectifying channel, subfamily J, member 16 | NM | ||
| Thyroid hormone receptor-β (Thrb) | NM | ||
| Phosphotriesterase related (Pter) | NM | ||
| Histamine n-methyltransferase (Hnmt) | NM | ||
| es-Type nucleoside transporter (Slc29a1) | NM |
Numbers in parentheses under Gene Name indicate numbers of GRE half-sites identified in rat and mouse, respectively. Sequence column presents regions containing half-sites with conservation in flanking regions. GRE half-sites are underlined, and nonconserved nucleotides are presented in lowercase letters. NM indicates no matches.