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Production of IFN-γ and IL-4 by splenocytes from mice vaccinated with ROP8-pVAX-1. Data represent the mean production of IFN-γ (A) and IL-4 (B) as determined by enzyme-linked immunosorbent assay (ELISA) of mice vaccinated with phosphate buffered saline (PBS), ROP8-pVAX-1, and pVAX-1 after 72 h of stimulation with total lysate antigen (TLA).
