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. 2013 May 1;88(5):897–907. doi: 10.4269/ajtmh.12-0467

Table 5.

Genotype frequencies and P values for chi-square tests for deviation from Hardy-Weinberg equilibrium for Anopheles gambiae S molecular forms collected in continental Equatorial Guinea, 2007 and 2009–2011*

2007 Pre-intervention Genotype P
Site L/L L/S S/S L/F S/F F/F N HO HE$ FIS$
 Akurenam 53 0 1 0 71 105 230 0.31 0.55 0.44 < 0.001
 Anisok 6 0 5 0 39 38 88 0.45 0.45 −0.01 < 0.001
 Cogo 67 0 5 0 15 22 109 0.12 0.51 0.77 < 0.001
 Ebebiyin 9 0 9 0 127 220 365 0.35 0.35 −0.02 < 0.001
 Mongomo 0 0 0 0 2 8 10 0.29 0.26 −0.09 1.000
 Ngolo 1 0 7 0 22 12 42 0.52 0.52 0.00 0.019
 Ukomba 13 0 5 0 10 12 40 0.21 0.66 0.68 < 0.001
 Yengue 14 1 18 7 92 77 209 0.48 0.53 0.10 < 0.001
Total 163 1 50 7 378 494 1,093
2009 Post-intervention Genotype P
Site L/L L/S S/S L/F S/F F/F N HO HE$ FIS$
 Aconibe 0 0 1 2 46 158 207 0.231 0.217 −0.08 0.470
 Akurenam 2 0 3 2 141 87 235 0.608 0.448 −0.36 < 0.001
 Anisok 0 0 1 0 18 92 111 0.16 0.165 0.02 1.000
 Cogo 10 0 5 9 132 192 348 0.405 0.388 −0.04 < 0.001
 Ebebiyin 5 1 5 1 70 228 310 0.232 0.261 0.11 < 0.001
 Mongomo 1 1 2 1 53 41 99 0.555 0.444 −0.25 < 0.001
 Ngolo 1 3 18 9 49 236 316 0.193 0.277 0.30 < 0.001
 Ukomba 0 0 0 0 47 22 69 0.68 0.45 −0.51 < 0.001
 Yengue 1 9 1 0 122 69 202 0.648 0.477 −0.36 < 0.001
Total 20 14 36 24 678 1,125 1,897
2010 Post-intervention Genotype P
Site L/L L/S S/S L/F S/F F/F N HO HE$ FIS$
 Aconibe 0 1 0 0 5 71 77 0.078 0.087 0.11 0.088
 Akurenam 5 19 4 35 41 5 109 0.87 0.663 −0.31 < 0.001
 Anisok 15 0 3 4 20 42 84 0.285 0.524 0.46 < 0.001
 Ebebiyin 3 1 4 1 82 177 268 0.313 0.307 −0.02 < 0.001
 Mongomo 3 0 1 3 50 306 363 0.146 0.155 0.06 < 0.001
 Ukomba 0 0 0 0 0 11 11 0 0 1.000
 Yengue 1 0 0 0 5 36 42 0.119 0.157 0.25 0.25
Total 27 21 12 43 203 648 954
2011 Post-intervention Genotype P
Site L/L L/S S/S L/F S/F F/F N HO HE$ FIS$
 Aconibe 3 3 4 2 20 46 78 0.32 0.42 0.25 < 0.001
 Akurenam 8 9 14 20 83 74 208 0.538 0.542 0.002
 Anisok 1 0 0 3 7 13 24 0.417 0.414 −0.01 0.988
 Cogo 21 6 8 6 48 91 180 0.333 0.511 0.35 < 0.001
 Ebebiyin 13 3 2 0 18 84 120 0.175 0.375 0.53 < 0.001
 Mongomo 6 3 15 24 155 273 476 0.382 0.379 0.00 < 0.001
 Ngolo 2 4 2 0 6 30 44 0.227 0.408 0.45 < 0.001
 Ukomba 0 0 2 0 5 12 19 0.263 0.371 0.30 0.235
 Yengue 5 3 6 32 49 74 169 0.50 0.488 −0.02 0.079
Total 59 31 53 87 391 697 1,318
*

Significant P values are indicated in bold.