Figure 2.

Dose-response curves for Ancylostoma caninum and Necator americanus to thiabendazole. Dose responses of A. caninum in egg hatch assays with thiabendazole, after 18 hours (A) obtained from three experiments B-2, B-3, and D where different conditions were used. In experiment B-3 eggs in anaerobic condition were refrigerated before the assay, whereas in experiment B-2 they were kept at room temperature. In experiment D, antifungal solution was added to the egg suspension before the assay. Panel B shows the dose responses of A. caninum to thiabendazole after 16 hours, obtained from experiment E. Panel C shows the dose responses of field N. americanus, after 16 hours exposure, obtained from three subjects naturally infected in Haiti (3010028, 3010022, and 3010019). All curves were obtained with the logit model; the dots represent the observed data obtained in all assays.