Table 4.

IFN-γ, TNF-α, IL-2, IL-4, IL-5, GM-CSF, IL-1β, and IL-8, were measured at 0 and 3 weeks^*

Cytokine	Mean (standard error of the mean)	P value by paired t test	P value by Wilcoxon signed-rank test for related samples
IFN-γ
@Time 0	166.4 (13.8)	< 0.001	< 0.001
@3 weeks	87.3 (5.8)
TNF-α
@Time 0	119.1 (6.18)	< 0.001	< 0.001
@3 weeks	71.0 (4.4)
IL-2
@Time 0	23.4 (2.1)	< 0.001	< 0.001
@3 weeks	13.8 (1.1)
IL-4
@Time 0	305.6 (14.6)	< 0.001	< 0.001
@3 weeks	190.1 (12.6)
IL-5
@Time 0	9.1 (0.6)	< 0.001	< 0.001
@3 weeks	5.7 (0.4)
GM-CSF
@Time 0	56.0 (3.9)	< 0.001	< 0.001
@3 weeks	30.4 (2.7)
IL-8
@Time 0	215.5 (39.7)	< 0.001	0.280
@3 weeks	960.1 (198.8)
IL-1β
@Time 0	27.4 (3.3)	0.386	0.453
@3 weeks	24.6 (2.4)

^*GM-CSF = granulocyte/macrophage-colony stimulating factor.