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Viral load in moribund STAT1 KO mice
| Organs* | Fraction of animals positive for ONNV | Time of death (dpi) | Viral load† (Log10 pfu/g) |
|---|---|---|---|
| Brain | 4/11 | 9–10 | 4.2–5.8 |
| Heart | 4/11 | 9–12 | 2.9–5.3 |
| Lung | 0/11 | N/A | NA |
| Liver | 0/11 | N/A | NA |
| Spleen | 0/11 | N/A | NA |
| Kidney | 0/11 | N/A | NA |
| Skeletal muscle | 5/11 | 9–12 | 3.0–5.6 |
6-week-old mice infected with 103 pfu of SG650.
Limit of detection = 2 log10 pfu/gram.
ONNV = O'nyong-nyong virus; pfu = plaque-forming units.
