Table 1. Baseline characteristics of the Normative Aging Study participants according to existing cancer diagnosis at baseline.

Variable	Cancer-free	Cancer
	n=517	All		Prostate cancer		Lung cancer		Colorectal cancer		Other cancers
		n=205	P valuea	n=85	P valuea	n=30	P valuea	n=23	P valuea	n=67	P valuea
Age (years), mean (SD)	72.2 (6.9)	73.1 (6.8)	0.099	74.2 (6.4)	0.010	71.0 (7.0)	0.387	74.3 (6.2)	0.133	72.1 (7.1)	0.985
Body Mass Index (kg/m2), mean (SD)	28.2 (4.2)	27.4 (3.9)	0.017	27.8 (3.8)	0.379	27.2 (3.9)	0.174	27.5 (4.2)	0.411	27.0 (3.8)	0.027
Race
White	494 (97.1)	201 (98.5)		84 (98.8)		29 (96.7)		23 (100.0)		65 (98.5)
Others	15 (2.9)	3 (1.5)	0.304	1 (1.2)	0.714	1 (3.3)	0.605	0 (0.0)	(-)	1 (1.5)	0.472
Education (years), n (%)
≤12	182 (35.2)	62 (30.2)		24 (28.2)		8 (26.7)		16 (69.6)		14 (20.9)
13-15	146 (28.2)	57 (27.8)		27 (31.8)		4 (13.3)		5 (21.7)		21 (31.3)
≥16	189 (36.6)	86 (42.0)	0.333	34 (40.0)	0.453	18 (60.0)	0.030	2 (8.7)	0.002	32 (47.8)	0.055
Ever smoked, n (%)
Never	146 (28.2)	65 (31.7)		31 (36.5)		10 (33.3)		8 (34.8)		16 (23.9)
Ever	371 (71.8)	140 (68.3)	0.356	54 (63.5)	0.123	20 (66.7)	0.548	15 (65.2)	0.497	51 (76.1)	0.453
Cumulative smoking (pack-years), mean (SD)	28.7 (23.1)	37.9 (41.8)	0.005	37.1 (46.4)	0.062	42.1 (33.3)	0.038	29.9 (24.8)	0.873	39.2 (43.9)	0.015
Alcohol drinkers (≥2 drinks/day), n (%)
No	427 (83.1)	163 (79.9)		65 (77.4)		21 (70.0)		20 (87.0)		57 (85.1)
Yes	87 (16.9)	41 (20.1)	0.317	19 (22.6)	0.205	9 (30.0)	0.068	3 (13.0)	0.626	10 (14.9)	0.680

^aStudent's t or Fisher's exact tests evaluating differences relative to cancer-free subjects