Six-month change in Continuous Performance Test — Identical Pairs, 4-digit condition by group (estimated marginal means, standard error bars). HC = healthy comparison group (N=17), Off/Off = clinical high risk for psychosis subjects off of medication at both time points (N=27), Off/AD = clinical high risk for psychosis subjects off medication at baseline and on an antidepressant at follow-up (N=15), Off/AP = clinical high risk for psychosis subjects off medication at baseline and on a second generation antipsychotic at follow-up (N=11).