. Author manuscript; available in PMC: 2013 Aug 27.

Published in final edited form as: Schizophr Res. 2012 Feb 28;137(0):110–117. doi: 10.1016/j.schres.2012.02.008

Table 1.

Baseline demographics and clinical characteristics.

Characteristic	HC (N=17)	OFF/OFF (N=27)	OFF/AD (N=15)	OFF/AP (N=11)	Test statistic	p value	Post-hoc contrasts
Age, y, mean (SD)	16.41 (2.26)	16.40 (2.00)	15.52 (1.94)	16.44 (1.52)	F_3,66=.80	.50	–
Estimated premorbid IQ, mean (SD)	110.41 (10.14)	106.7 (10.21)	103.73 (12.92)	108.18 (7.31)	F_3,66=1.14	.34	–
Estimated current IQ, mean (SD)	108.29 (18.75)	108 (16.93)	101.73 (10.22)	95.09 (13.93)	F_3,66=2.22	.09	–
Years of education, mean (SD)	10.65 (2.26)	9.89 (2.03)	9.33 (1.99)	10.27 (1.74)	F_3,66=1.20	.32	–
Gender, no. (%)
Female	8 (47.1)	6 (22.2)	5 (33.3)	2 (18.2)	$χ_{3}^{2} = 3.94$	.27	–
Male	9 (52.9)	21 (77.8)	10 (66.7)	9 (81.8)
Handedness, right, no. (%)	14 (82.4)	23 (85.2)	13 (86.7)	10 (90.9)	$χ_{3}^{2} = .42$	.94	–
Race
White, no. (%)	11 (64.7)	18 (66.7)	8 (53.3)	7 (63.6)	$χ_{3}^{2} = .78$	.86	–
Ethnic origin
Hispanic, no. (%)	2 (11.8)	7 (25.9)	2 (13.3)	0 (0.0)	$χ_{3}^{2} = 4.44$	22	–
Anxiety score, mean (SD)^a	0.09 (0.11)	0.19 (0.14)	0.19 (0.20)	0.13 (0.09)	F_3,62=1.91	.14	–
Depression score, mean (SD)^b	0.08 (0.08)	0.24 (0.15)	0.27 (0.14)	0.19 (0.10)	F_3,60=6.22	b.01	NC<OFF/OFF, OFF/AD, OFF/AP
SIPS score, mean (SD)
Positive	1.00 (1.87)	7.52 (4.56)	6.53 (4.41)	6.27 (3.29)	F_3,66=10.74	<.001	NC<OFF/OFF, OFF/AD, OFF/AP
Negative	1.88 (1.69)	13.19 (4.81)	16.6 (6.05)	13.91 (7.4)	F_3,66=27.08	<.001	NC<OFF/OFF, OFF/AD, OFF/AP
Disorganized	0.76 (1.52)	4.33 (3.11)	6.2 (4.16)	4.09 (3.14)	F_3,66=8.78	<.001	NC<OFF/OFF, OFF/AD, OFF/AP
General	0.88 (1.62)	7.85 (4.97)	8.33 (3.18)	6.73 (3.77)	F_3,66=14.19	<.001	NC<OFF/OFF, OFF/AD, OFF/AP
DSM-IV diagnoses, no. (%)
Mood^c	–	15 (55.6)	9 (60.0)	5 (45.5)	$χ_{2}^{2} = .56$	.76	–
Anxiety^d	–	16 (59.3)	11 (73.3)	7 (63.6)	$χ_{2}^{2} = .83$	.66	–
Substance^e	–	3 (11.1)	0 (0.0)	2 (18.2)	$χ_{2}^{2} = 2.64$	.27	–
Time to retest, months, mean (SD)	5.27 (3.27)	6.82 (2.27)	4.88 (1.19)	6.67 (1.78)	F_3,66=3.12	.03	OFF/AD<OFF/OFF

Note: SIPS, structured interview for prodromal syndromes; DSM-IV, Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition.

Percentage of the maximum possible score on BDI/CDI.

Percentage of the maximum possible score on BAI.

DSM-IV defined diagnosis of major depressive disorder, dysthymic disorder, or depressive disorder, not otherwise specified (NOS).

DSM-IV defined diagnosis of panic disorder, posttraumatic stress disorder, obsessive–compulsive disorder, generalized anxiety disorder, anxiety disorder NOS, or phobias including simple phobia and social phobia.

DSM-IV defined diagnosis of alcohol, amphetamine, cannabis, cocaine, hallucinogen, opioid, or polysubstance abuse.