. Author manuscript; available in PMC: 2014 Apr 1.

Published in final edited form as: J Vasc Surg Venous Lymphat Disord. 2013 Mar 14;1(2):117–1125. doi: 10.1016/j.jvsv.2012.09.001

Table VII.

Diagnosing LE-DVT

Biomarker	Specificity	Sensitivity	Positive predictive value	Negative predictive value
sP-sel ≥90 ng/mL + Wells ≥2	97.5%	27.4%	91%	NA
D-dimer ≥500 ng/mL + Wells ≥2	65.5%	82.3%	69%	NA
sP-sel ≤60 ng/mL + Well’s <2	31.1%	91.1%	NA	79%
D-dimer ≤500 ng/mL + Wells <2	29.5%	98.2%	NA	95%

DVT, Deep venous thrombosis; LE, lower extremity; sP-sel, soluble P-selectin.