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. 2013 Jul 25;24(9):1493–1502. doi: 10.1681/ASN.2012080831

Table 3.

Association (HR and 95% CI) of PDC Frequency and Duration with All-Cause Mortality, after Various Levels of Adjustment

All-Cause Mortality Model 0 Model 1 Model 2 Model 3 Model 4 Model 4a Model 4b
PDC frequency
 Low frequency (less than weekly) 1.08 (0.99 to 1.19) 1.11 (1.01 to 1.22) 1.11 (1.01 to 1.23) 1.11 (1.01 to 1.22) 1.08 (0.98 to 1.19) 1.11 (1.01 to 1.23)
 Intermediate frequency (weekly) 1.10 (1.00 to 1.21) 1.07 (0.97 to 1.19) 1.08 (0.97 to 1.19) 1.07 (0.97 to 1.18) 1.06 (0.96 to 1.16) 1.06 (0.96 to 1.17)
 High frequency (more than weekly) 1.00 (reference) 1.00 (reference) 1.00 (reference) 1.00 (reference) 1.00 (reference) 1.00 (reference)
 P for trend across categories 0.07 0.04 0.02 0.04 0.11 0.03
PDC duration
 Per 5 min shorter duration 1.08 (1.04 to 1.12) 1.04 (1.00 to 1.08) 1.04 (1.00 to 1.08) 1.05 (1.01 to 1.09) 1.04 (1.01 to 1.08) 1.05 (1.01 to 1.09)
P for duration as continuous variable <0.001 0.03 0.03 0.02 0.03 0.01
 Categorical analysis
  Short duration (≤5 min) 1.23 (1.10 to 1.38) 1.11 (1.00 to 1.24) 1.11 (0.99 to 1.24) 1.12 (1.00 to 1.25) 1.11 (0.99 to 1.24) 1.13 (1.01 to 1.27)
  Intermediate duration (6–10 min) 1.17 (1.03 to 1.32) 1.10 (0.98 to 1.24) 1.10 (0.98 to 1.24) 1.09 (0.97 to 1.23) 1.11 (0.99 to 1.25) 1.13 (1.00 to 1.28)
  Long duration (>10 min) 1.00 (reference) 1.00 (reference) 1.00 (reference) 1.00 (reference) 1.00 (reference) 1.00 (reference)

Model 0: stratified by phase and region and accounted for facility clustering effects; model 1: model 0 + age, sex, race, body mass index, dialysis vintage, and 14 comorbid conditions; model 2: model 1 + education, employment and living status, marital status; model 3: model 2 + patient-doctor ratio, patient-staff ratio, and hospital-based units; model 4: model 3 + Kt/V, treatment time, serum albumin, calcium, phosphorus, hemoglobin, and vascular access; model 4a: model 4 + PDC duration (continuous); model 4b: model 4 + PDC frequency (categories).