TABLE 1.
Patient | Isolate | Yra | Prior therapyb | Site of isolationc | MIC/MFCd (μg/ml)
|
MEC of CAS (μg/ml) | ||
---|---|---|---|---|---|---|---|---|
ITZ | VRZ | AMB | ||||||
1 | W1 | 1995 | FLU, AMB | Lung | 0.5/1 | 2/4 | 2/4 | 16 |
W2 | 1995 | FLU, AMB | Kidney | 1/2 | 2/4 | 1/2 | 4 | |
2 | W3 | 1998 | FLU | Mouth | 1/2 | 2/4 | 2/2 | 16 |
W4 | 1998 | FLU | Lung | 1/2 | 2/4 | 1/2 | >32 | |
3 | W5 | 1999 | FLU | Lung | 1/2 | 2/2 | 2/4 | 16 |
4 | W6 | 2000 | AMB, VRZ | Lung | 1/2 | 2/4 | 1/4 | 32 |
W7 | 2000 | AMB, VRZ | Mouth | 1/2 | 2/4 | 2/4 | 32 |
Year during which isolates were recovered from the indicated site.
Antifungal therapy prior to day of infection.
Isolates recovered from either bronchoalveolar lavage or lung biopsy specimens are indicated as “lung.” Kidney isolates were recovered at autopsy.
MICs shown were determined by the NCCLS method, as described in Materials and Methods.