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Scatter plots of the relationships between (A) cerebrospinal fluid (CSF) sorbitol and (B) CSF fructose concentrations and rank-transformed deep white matter hyperintensity (WMH) volumes in bipolar disorder patients; n = 20. Higher rank means greater deep WMH volume (50 = highest). R2 = 0.293 for CSF sorbitol and 0.195 for CSF fructose.
