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. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2012 Aug 9;4(6):605–619. doi: 10.1002/wnan.1186

Figure 7.

Figure 7

Labeling of dopamine transporter (DAT) with ligand conjugated-QDots in live HeLa cells. (Left) Streptavidin-conjugated QDots were used to label DATs previously exposed to a biotinylated, PEGylated cocaine analog. (Upright) chemical structure of the DAT ligand used in the study. (A1) QDot labeling of membrane DATs in a live HeLa cell. (B1) QDot-bound DATs underwent acute redistribution from the plasma membrane to intracellular compartments as a result of protein kinase C (PKC) activation. (Reprinted with permission from Ref 48. Copyright 2011 American Chemical Society)