Table 4.

Change in gene expression in lumbar DRG and TG of NRTN-OE mice

Gene assayeda	DRG (percentage change)	TG (percentage change)
ASIC2a	95*	125*
ASIC2b	20	13
GFRα1	6.0	−17
GFRα2	62*	98*
GFRα3	−32*	−28*
Nav 1.8	13	ND
P2X3	84*	42*
p75	−5.0	−11
Piezo 2	15	ND
Ret	77*	144*
Runx1	38*	76*
TrkA	−23	−13
TRPA1	74*	42*
TRPM8	44*	84*
TRPV1	−22	−10

^aASIC2a, GFRα2, P2X₃, Ret, Runx1, and TRPM8 were increased in ganglia of NRTN-OE mice relative to WT mice. ND, Not determined.

*Significant difference (p < 0.05; t test with Bonferroni correction).