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IRF9 mediates the antiproliferative effects of IFNα2. Proliferation was measured by [3H]thymidine incorporation assay in LNCaP, LNCaP-IL6+, and PC3 cells after downregulation of IRF9 and additional treatment with 1000 U/ml IFNα2 after 72 h. Data represent mean±s.e.m. from three independent experiments. *P<0.05; **P<0.01; ***P<0.001.
