Table 3.

Ruxolitinib combination therapy – clinical studies

Combination agent	Study title	Trial identifier
Lenalidomide	Ruxolitinib and Lenalidomide for Patients with Myelofibrosis	NCT01375140
Pomalidomide	Ruxolitinib and Pomalidomide Combination Therapy in Patients with Primary and Secondary MF (POMINC)	NCT01644110
Danazol	Ruxolitinib Phosphate and Danazol in Treating Anemia in Patients with Myelofibrosis	NCT01732445
Panobinostat	Panobinostat and Ruxolitinib in Myelofibrosis (PRIME Trial)	NCT01693601
Buparlisib (BKM120)	A Study to Find the Maximum Tolerated Dose of the Experimental Combination of the Drugs INC424 and BKM120 in Patients with Primary or Secondary Myelofibrosis	NCT01730248
LDE225	A Phase Ib/II Dose-finding Study to Assess the Safety and Efficacy of LDE225 + INC424 in Patients with MF	NCT01787552
Stem cell transplantation	Ruxolitinib Prior to Transplant in Patients with Myelofibrosis	NCT01790295

Abbreviation: MF, myelofibrosis.