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Human epithelial lining fluid (ELF) levofloxacin concentrations and the corresponding pharmacokinetic profiles observed for the isolates in the in vitro simulations. Error bars represent the standard deviations for the patient epithelial lining fluid levofloxacin concentrations. The values on the x axis are times (in hours). ⧫, isolate 53; ×, isolate 93; +, isolate 1610; ○, isolate 1312; *, concentration in patient epithelial lining fluid; ▴, isolate 1911; •, isolate 1386.
