TABLE 1.
Preexperimental phenotypic and genotypic profiles of the S. pneumoniae isolates
| S. pneumoniae isolate | Mutation locus or loci for levofloxacin | Levofloxacin MIC (μg/ml) | Mutation locus or loci for moxifloxacin | Moxifloxacin MIC (μg/ml) |
|---|---|---|---|---|
| 53 | None | 1.0 | None | 0.125 |
| 1911 | parC + gyrA | 16 | parC + gyrA | 2 |
| 93 | parC + gyrA + parE | 128 | parC + gyrA + parE | 8 |
| 1312 | parC + parE | 2 | parC + parE | 0.25 |
| 1386 | parC + parE | 2 (32)a | NAb | (4) |
| 1610 | parC | 2 (32) | NA | (4) |
a
The values in parentheses are the postexperimental MICs (see Table 4).
b
NA, not applicable, as in vitro experimentation was not performed with these isolates and moxifloxacin.