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Simvastatin increase LC3B and calponin expression in coronary arteries. Mice were intragastrically fed simvastatin for two weeks with or without mevalonate. Frozen sections of mouse hearts were stained with Alexa488-anti-α-smooth muscle actin (α-SMA) and Alexa555-anti-LC3B or Alexa555-anti-calponin antibodies. Displayed are representative confocal microscopic images showing the expression of LC3B (A) or calponin (B) in coronary arteries (n=5).
