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. 2013 Sep;32(9):524–530. doi: 10.1089/dna.2013.2052

Table 1.

Results from the Computational Analysis of the p.L162P DHH-N Mutant Form of Desert Hedgehog

Server Score Consequence
MU-Pro Pseudo delta delta G: −4.85 Decrease of the stability of protein structure
SDM Delta delta G: −4.87 This mutation is predicted to be highly destabilizing and causes protein malfunction and disease
  Confidence score: −0.18585369  
SNAP Reliability: 6 This is considered a non-neutral mutation, can be related to protein malfunction
  Expected accuracy: 93%  

DHH, Desert hedgehog.