Table 1. Comparison of ultrastructural characteristics of bushy cells and primary auditory nerve terminals of the rostral and caudal mouse AVCN.
|
Parameter
|
Range (max/min) | Median | p-value | |
|---|---|---|---|---|
|
Cell Body
| ||||
| Aspect ratio (long vs. short axis) | aAVCN | 1.565/1.060 | 1.282 | 0.843 |
| pAVCN | 1.576/1.090 | 1.298 | ||
| Number mitochondria per 10 µm2 | aAVCN | 1.160/0.769 | .980 | 0.001* |
| pAVCN | 1.047/0.552 | .747 | ||
| Average mitochondria size (per cell) | aAVCN | 0.124/0.055 | .099 | 0.002* |
| pAVCN | 0.146/0.093 | .113 | ||
| Number of terminals per 10 µm (perimeter) | aAVCN | 4.896/2.652 | 3.80 | 0.114 |
| pAVCN | 4.270/2.633 | 2.20 | ||
| Percent perimeter apposed by terminals | aAVCN | 87.792/55.037 | 73.614 | p<0.001* |
| pAVCN | 75.073/48.90 | 58.991 | ||
| Percent primary terminals | aAVCN | 68.421/30.0 | 46.310 | 0.0079* |
| pAVCN | 89.470/34.780 | 68.586 | ||
| Primary Auditory Nerve Terminals | ||||
| Primary profile cross sectional area (µm2) | aAVCN | 12.379/0.590 | 2.204 | 0.085 |
| pAVCN | 15.983/0.295 | 1.323 | ||
| PSD length (µm) | aAVCN | 0.494/0.159 | 0.314 | 0.502 |
| pAVCN | 0.586/0.169 | 0.330 | ||
| PSD curvature | aAVCN | 0.487/0.098 | 0.249 | 0.903 |
| pAVCN | 0.799/0.110 | 0.233 | ||
| Percent mitochondria area | aAVCN | 52.53/0 | 20.410 | 0.396 |
| pAVCN | 34.201/0 | 19.252 | ||
| Number of SVs per µm2 within 0.5 µm of PSD | aAVCN | 271.277/54.054 | 131.098 | p<0.001* |
| pAVCN | 180.064/29.101 | 105.456 | ||
* statistically significant , p<0.0083