Table 2. The effects of donor CYP3A5 rs776746 and IL6 rs1800796 polymorphisms on tacrolimus C/D ratios.
Week 1 | Week 2 | Week 3 | Week 4 | |||||||
SNPs | Genotypes | N | C/D ratio | P | C/D ratio | P | C/D ratio | P | C/D ratio | P |
rs776746 | GG | 46 | 295.1±413.2 | 0.006 | 130.8±130.9 | 0.085 | 121.2±81.1 | 0.028 | 148.8±126.9 | 0.001 |
GA+AA | 49 | 199.0±209.8 | 102.8±101.1 | 88.7±102.5 | 85.6±75.5 | |||||
rs1800796 | CC | 41 | 221.2±275.0 | 0.314 | 105.2±91.1 | 0.032 | 97.4±76.1 | 0.021 | 95.1±83.7 | 0.113 |
CG+GG | 54 | 240.9±318.7 | 132.3±119.0 | 127.4±125.3 | 133.2±119.3 |