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. 2013 Aug 26;8(8):e73405. doi: 10.1371/journal.pone.0073405

Table 2. The effects of donor CYP3A5 rs776746 and IL6 rs1800796 polymorphisms on tacrolimus C/D ratios.

Week 1 Week 2 Week 3 Week 4
SNPs Genotypes N C/D ratio P C/D ratio P C/D ratio P C/D ratio P
rs776746 GG 46 295.1±413.2 0.006 130.8±130.9 0.085 121.2±81.1 0.028 148.8±126.9 0.001
GA+AA 49 199.0±209.8 102.8±101.1 88.7±102.5 85.6±75.5
rs1800796 CC 41 221.2±275.0 0.314 105.2±91.1 0.032 97.4±76.1 0.021 95.1±83.7 0.113
CG+GG 54 240.9±318.7 132.3±119.0 127.4±125.3 133.2±119.3