Table 4. Combined analysis of donor CYP3A5 rs776746 allele A, IL6 rs1800796 allele C, and recipient CYP3A5 rs776746 allele A on tacrolimus C/D ratios.

		Week 1		Week 2		Week 3		Week 4
Numa	N	C/D ratio	P	C/D ratio	P	C/D ratio	P	C/D ratio	P
≤1	19	460.0±420.9	0.001	186.5±121.7	0.001	177.7±140.8	<0.001	172.5±177.6	<0.001
2−3	61	242.4±261.0		117.2±96.4		109.6±88.7		107.2±81.1
≥4	15	91.8±167.9		59.0±93.6		67.7±49.0		73.4±47.9

^a“Num” indicates the number of alleles associated with fast metabolism patients carrying.