Table 2. Physiological markers in diabetic mice in the presence and absence of plumbagin.

	Non Diabetic (i)	Diabetic-DMSO (ii)	Diabetic-Nox4 inhibitor iii	P value (ii vs i)	P value (iii vs i)	P value (iii vs ii)
Serum Creatinine (µmol/L)	13.3±1.2	25.3±4.0#	14.8±1.1#	0.001	0.55	0.004
Cr Clearance Rate (ml/min)	2.0±6.2×104	1.56±4.0×104	1.9±2.0×104	0.4	0.8	0.58
Urine Albumin Creatinine Ratio (mg/mmol)	3.4±0.4	13.2±1.5##	4.8±1.1#	0.0002	0.2	0.0006
Kidney/Body Weight Ratio (g/g)	6.9±0.2×10−3	9.5±0.4×10−3ψ	8.1±0.1×10−3*	<0.0001	0.01	0.009
24 hr Urine Volume (ml)	0.7±0.15	6.4±2.4#	3.9±1.6	0.005	0.06	0.21
Weight Gain (Fold change over original weight)	1.3±0.27	1.0±0.03ψ	1.2±0.05#	<0.0001	0.03	0.004
Blood Glucose level mmol/L	11.1±0.6	23.0±2.4#	21.1±3.2	0.0017	0.0001	0.33