Table 4. Distribution of all identified Claudin14 SNPs in the low and high urinary Ca2+ excretion groups with unadjusted Chi square P values.
| Chr. Position | SNP ID (rs…) | SNP class | Nucleotide | Low urine Ca2+ | High urine Ca2+ | P |
| 37833330 | . | missense | c.664G>T | 2.2% (16/710) | 1.5% (8/520) | 0.41 |
| 37833331 | . | silent | c.663G>A | 0.0% (0/710) | 0.2% (1/520) | - |
| 37833934 | . | silent | c.60C>T | 0.1% (1/710) | 0.2% (1/520) | - |
| 37833931 | 117560775 | silent | c.63G>A | 1.4% (10/710) | 3.2% (17/520) | 0.03 |
| 37833694 | 113350364 | silent | c.300C>T | 0.4% (3/710) | 0.0% (0/520) | - |
| 37833699 | . | missense | c.295G>A | 0.0% (0/710) | 0.3% (1/520) | - |
| 37833751 | 219779 | silent | c.243C>T | 24.2% (172/710) | 23.8% (124/520) | 0.89 |
| 37833979 | . | silent | c.15C>T | 0.0% (0/710) | 0.2% (1/520) | - |
| 37833809 | . | missense | c.185A>G | 0.4% (3/710) | 0.0% (0/520) | - |
| 37833892 | . | silent | c.102G>A | 0.1% (1/710) | 0.0% (0/520) | - |
| 37833865 | . | silent | c.129C>T | 0.3% (2/710) | 0.0% (0/520) | - |
| 37833506 | . | missense | c.488C>T | 0.3% (2/710) | 0.2% (1/520) | - |
| 37833983 | 113831133 | missense | c.11C>T | 4.1% (29/710) | 1.1% (6/520) | 0.003 |
| 37833976 | . | silent | c.18G>A | 0.3% (2/710) | 0.0% (0/520) | - |
| 37833661 | 74934405 | silent | c.333A>C | 4.1% (29/710) | 4.4% (23/520) | 0.77 |
| 37833304 | . | silent | c.690C>T | 0.1% (1/710) | 0.1% (1/520) | - |
| 37833307 | 219780 | silent | c.687G>A | 18.4% (131/710) | 18.9% (98/520) | 0.82 |
The missense variant rs113831133, highlighted in bold, was more frequent among individuals with lower urinary Ca2+ excretion. This association did not reach statistical significance when adjusted for multiple comparisons.