Skip to main content
. 2004 Apr;48(4):1272–1280. doi: 10.1128/AAC.48.4.1272-1280.2004

TABLE 2.

Cumulative radioactivity excretion in urine and feces of caspofungin in rats, rabbits, and monkeys after a single intravenous dosea

Species Dose (mg/kg) Collection period (days) % of dose excreted in feces % of dose excreted in urine Total % of dose excreted
Rat 2 12 29.4 ± 2.5 42.1 ± 1.3 71.5 ± 1.8
Rabbit 5 28 50.8 ± 3.0 36.0 ± 4.4 86.8 ± 2.9
Monkey 5 28 36.2 ± 0.7 45.4 ± 0.3 81.6 ± 1.1
a

Data are presented as means ± standard deviation for three rats and monkeys and four rabbits.