Skip to main content
. 2013 Aug 26;8(8):e68457. doi: 10.1371/journal.pone.0068457

Table 1. Main characteristics of all studies included in the meta-analysis.

First author/year Country Ethnicity SNPS GM SC Matching
Ratnasinghe [25] 2001 China Asian Arg399Gln TaqMan PB Age/sex
Ratnasinghe [25] 2001 China Asian Arg194Trp TaqMan PB Age/sex
Ratnasinghe [25] 2001 China Asian Arg280His TaqMan PB Age/sex
David-Beabes [26] 2001 USA Caucasian Arg399Gln PCR-RFLP PB Age/sex/ethnicity
David-Beabes [26] 2001 USA Caucasian Arg194Trp PCR-RFLP PB Age/sex/ethnicity
David-Beabes [26] 2001 USA African Arg399Gln PCR-RFLP PB Age/sex/ethnicity
David-Beabes [26] 2001 USA African Arg194Trp PCR-RFLP PB Age/sex/ethnicity
David-Beabes [27] 2001 USA Caucasian T241M PCR-RFLP PB Age/sex/ethnicity
David-Beabes [27] 2001 USA African T241M PCR-RFLP PB Age/sex/ethnicity
Divine [28] 2001 USA Caucasian Arg399Gln PCR-RFLP HB No clear
Chen [29] 2002 China Asian Arg399Gln PCR PB Age/sex
Chen [29] 2002 China Asian Arg194Trp PCR PB Age/sex
Park [30] 2002 Korea Asian Arg399Gln PCR-RFLP HB Age
Misra [31] 2003 USA Caucasian Arg399Gln PCR PB Age
Misra [31] 2003 USA Caucasian Arg280His PCR PB Age
Misra [31] 2003 USA Caucasian T241M PCR PB Age
Zhou [33] 2003 USA Caucasian Arg399Gln PCR-RFLP PB No clear
Wang [34] 2003 USA Mixed T241M PCR-RFLP PB Age/ethnicity/gender
Ito [35] 2004 Japan Asian Arg399Gln PCR-CTTP HB Age/sex
Popanda [36] 2004 German Caucasian Arg399Gln PCR HB No clear
Popanda [36] 2004 German Caucasian T241M PCR HB No clear
Harms [38] 2004 German Caucasian Arg399Gln PCR HB Age/ethnicity/gender
Harms [38] 2004 German Caucasian T241M PCR HB Age/ethnicity/gender
Jacobsen [39] 2004 Danish Caucasian T241M PCR PB No clear
Zhang [40] 2005 China Asian Arg399Gln PCR-RFLP PB Age/sex
Hung [41] 2005 Europe Caucasian Arg399Gln PCR HB Age/sex/area
Hung [41] 2005 Europe Caucasian Arg194Trp PCR HB Age/sex/area
Hung [41] 2005 Europe Caucasian Arg280His PCR HB No clear
Hung [41] 2005 Europe Caucasian T241M PCR HB No clear
Vogel [42] 2004 Danish Caucasian Arg399Gln PCR PB No clear
Vogel [42] 2004 Danish Caucasian Arg280His PCR PB No clear
Schneider [43] 2005 German Caucasian Arg399Gln PCR HB No clear
Schneider [43] 2005 German Caucasian Arg194Trp PCR HB No clear
Schneider [43] 2005 German Caucasian Arg280His PCR HB No clear
Shen [44] 2005 China Asian Arg399Gln PCR PB Age/sex/village
Shen [44] 2005 China Asian Arg194Trp PCR PB Age/sex/village
Shen [44] 2005 China Asian Arg280His PCR PB Age/sex/village
Chan [45] 2005 China Asian Arg399Gln PCR-RFLP HB Age/sex
Chan [45] 2005 China Asian Arg194Trp PCR-RFLP HB Age/sex
Hu [47] 2005 China Asian Arg399Gln PCR HB Age/sex/area
Hu [47] 2005 China Asian Arg194Trp PCR HB Age/sex/area
Hu [47] 2005 China Asian −77T>C PCR-RFLP HB Age/sex/area
Zienolddiny [48] 2006 Norway Caucasian Arg399Gln TaqMan PB Age/sex/smoking
Zienolddiny [48] 2006 Norway Caucasian Arg194Trp TaqMan PB Age/sex/smoking
Zienolddiny [48] 2006 Norway Caucasian Arg280His TaqMan PB Age/sex/smoking
Zienolddiny [48] 2006 Norway Caucasian T241M TaqMan PB Age/sex/smoking
Matullo [49]2006 Europe Caucasian Arg399Gln TaqMan PB Age/sex/smoking
Matullo [49]2006 Europe Caucasian T241M TaqMan PB Age/sex/smoking
Hao [50] 2006 China Asian Arg399Gln PCR-RFLP PB Age/sex/ethnicity
Hao [50] 2006 China Asian Arg194Trp PCR-RFLP PB Age/sex/ethnicity
Hao [50] 2006 China Asian Arg280His PCR-RFLP PB Age/sex/ethnicity
Hao [50] 2006 China Asian −77T>C PCR-RFLP PB Age/sex/ethnicity
Landi [51] 2006 Europe Caucasian Arg399Gln PCR HB Age/sex/center/area
Landi [51] 2006 Europe Caucasian Arg194Trp PCR HB Age/sex/center/area
Landi [51] 2006 Europe Caucasian Arg280His PCR HB Age/sex/center/area
Landi [51] 2006 Europe Caucasian T241M PCR HB Age/sex/center/area
Ryk [52] 2006 Swede Caucasian Arg399Gln PCR PB Age/sex/smoking
Ryk [52] 2006 Swede Caucasian T241M TaqMan PB Age/sex/smoking
De Ruyck [53] 2007 Belgium Caucasian Arg399Gln PCR-RFLP HB Age/sex
De Ruyck [53] 2007 Belgium Caucasian Arg194Trp PCR-RFLP HB Age/sex
De Ruyck [53] 2007 Belgium Caucasian Arg280His PCR-RFLP HB Age/sex
De Ruyck [53] 2007 Belgium Caucasian −77T>C PCR-RFLP HB Age/sex
Pachouri [54] 2007 India Asian Arg399Gln PCR-RFLP PB No clear
Pachouri [54] 2007 India Asian Arg194Trp PCR-RFLP PB No clear
Yin [55] 2007 China Asian Arg399Gln PCR-RFLP HB Age/gender/ethnicity
Yin [55] 2007 China Asian Arg194Trp PCR-RFLP HB Age/gender/ethnicity
Yin [55] 2007 China Asian Arg280His PCR-RFLP HB Age/gender/ethnicity
Lopez-Cima [56] 2007 Spain Caucasian Arg399Gln PCR-RFLP HB Age/gender/ethnicity
Lopez-Cima [56] 2007 Spain Caucasian T241M PCR-RFLP HB Age/gender/ethnicity
Zhang [57] 2007 China Asian T241M PCR HB No clear
Improta [58] 2008 Italy Caucasian Arg399Gln PCR-RFLP HB Age/sex
Improta [58] 2008 Italy Caucasian Arg194Trp PCR-RFLP HB Age/sex
Improta [58] 2008 Italy Caucasian T241M PCR-RFLP HB Age/sex
Li [59] 2008 China Asian Arg399Gln PCR-RFLP HB Age
Li [59] 2008 China Asian Arg194Trp PCR-RFLP HB Age
Li [59] 2008 China Asian Arg280His PCR-RFLP HB Age
Li [59] 2008 China Asian −77T>C PCR-RFLP HB Age
Hsieh [61] 2009 China Asian −77T>C PCR HB No clear
Cote [62] 2009 USA Caucasian Arg399Gln PCR PB Age/race
Cote [62] 2009 USA African Arg399Gln PCR PB Age/race
Qian [63] 2010 China Asian T241M PCR HB Age/gender
Qian [63] 2010 China Asian Arg399Gln PCR HB Age/gender
Tanaka [64] 2010 Japan Asian Arg194Trp PCR HB Age/sex/ethnicity
Kim [65] 2010 Korea Asian Arg399Gln PCR HB No clear
Kim [65] 2010 Korea Asian Arg280His PCR HB No clear
Osawa [66] 2010 Japan Asian T241M PCR-RFLP HB No clear
Osawa [66] 2010 Japan Asian Arg399Gln PCR-RFLP HB No clear
Huang [67] 2011 China Asian T241M PCR-RFLP HB Age/sex
Janik [68] 2011 Poland Caucasian Arg399Gln PCR-SSCP HB Age/sex/smoking/diet
Janik [68] 2011 Poland Caucasian Arg194Trp PCR-SSCP HB Age/sex/smoking/diet
Janik [68]2011 Poland Caucasian Arg280His PCR-SSCP HB Age/sex/smoking/diet
Li [69] 2011 China Asian Arg399Gln PCR-CTTP HB Age/sex/area
Wang [70]2012 China Asian Arg194Trp PCR-RFLP HB Age/sex/area
Wang [70]2012 China Asian Arg280His PCR-RFLP HB Age/sex/area
Wang [70]2012 China Asian Arg399Gln PCR-RFLP HB Age/sex/area
Chikako [71] 2012 Japan Asian Arg399Gln PCR-RFLP HB Age/sex
Chikako [71] 2012 Japan Asian T241M PCR-RFLP HB Age/sex
Sreeja [72] 2008 India Asian Arg399Gln PCR-RFLP HB Age/sex
Chang [73] 2009 USA Caucasian Arg399Gln PCR-RFLP PB Age/sex/area
Chang [73] 2009 USA Caucasian Arg194Trp PCR-RFLP PB Age/sex/area
Chang [73] 2009 USA Caucasian Arg280His PCR-RFLP PB Age/sex/area
Chang [73] 2009 USA African Arg399Gln PCR-RFLP PB Age/sex/area
Chang [73] 2009 USA African Arg194Trp PCR-RFLP PB Age/sex/area

SNPS Single-nucleotide polymorphism studied, GM Genotyping method, SC Source of controls, SSCP Single-strand conformation polymorphism, CTPP Contronting two-pair primers, SNPS Single-nucleotide polymorphism studied, PB Population-based study, HB Hospital-based study.