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. 2013 Aug 26;8(8):e72059. doi: 10.1371/journal.pone.0072059

Table 1. Plasma levels of cytokines, chemokines and growth factors (in pg/ml) at baseline and after 24 h of reperfusion.

Marker Baseline NaCl C1 INH
EPO 278.9±183.2 729.0±427.7 346.9±353.1
CXCL1 93.0±14.5 127.4±77.0 78.3±68.8
IFN-γ 57.6±34.9 120.3±100.2 19.1±11.4*
IL-1α 9.0±4.9** 83.1±44.9 16.9±10.3*
IL-4 22.6±11.4 57.5±39.3 8.3±4.2
IL-5 96.5±11.2 172.7±73.6 108.3±23.7
IL-7 69.1±22.9** 240.9±98.3 67.2±42.0**
IL-10 306.6±51.3 776.3±508.0 279.1±94.2
IL-17A 7.0±1.5** 27.1±14.0 8.3±3.4**
IL-18 1103.0±720.6** 4155.0±1390.0 1115.0± 80.4**
MCP-1 425.0±58.0* 1693.0±982.4 1905.0±638.3
MIP-1α 1097.0±968.0* 4629.0±3045.0 1203.0±762.0*
MIP-3α 10.0±8.6** 48.0 ± 20.2 12.0±9.5**
RANTES 164.0±89.1 310.2±309.7 389.0±442.7
TNF-α 19.1±6.1 40.4±24.9 9.1±7.5*
VEGF 12.0±4.9 16.0±6.0 11.4±2.0
M-CSF 293.6±50.8 381.2±117.1 459.1±79.2

EPO indicates Erythropoietin; CXCL1, Chemokine (C-X-C motif) Ligand 1; IFN-gamma, Interferon-gamma; IL, Interleukin; MCP-1, Monocyte chemotactic protein-1; MIP, Macrophage inflammatory protein; RANTES, Regulated and normal T cell expressed and secreted; TNF-α, Tumor necrosis factor-α; VEGF, Vascular endothelial growth factor; M-CSF, Macrophage colony-stimulating factor. Values are mean ± SD. P<0.05*; P<0.01** by ANOVA with Dunnett's post test vs. NaCl. Multiplex analysis of the shown markers was performed using a standard rat 24-plex panel from Bio-Rad. IL-1β, IL-2, IL-6, IL12p70, IL-13, G-CSF, GM-CSF were below detection level and are not listed.