Table 1. Differentially expressed genes between wild-type and ΔmU50(HG-b) mouse B-lymphocytes detected by a comparative microarray analysis.
Gene Symbol | Gene Title | Ratio | Z-score |
Up-regulated in ΔmU50(HG-b) mice | |||
Dvwa * | dual von Willebrand factor A domains | 2.56 | 10.64 |
Xlr3a | X-linked lymphocyte-regulated 3A | 2.63 | 9.27 |
Slc15a2 | solute carrier family 15 (H+/peptide transporter), member 2 | 2.24 | 9.17 |
Hspa1b | heat shock protein 1B | 1.86 | 7.06 |
Hsph1 | heat shock 105 kDa/110 kDa protein 1 | 1.77 | 6.54 |
Cpt1a | carnitine palmitoyltransferase 1a, liver | 1.69 | 5.98 |
Siglech | sialic acid binding Ig-like lectin H | 1.85 | 5.91 |
Mgl1 | macrophage galactose N-acetyl-galactosamine specific lectin 1 | 1.77 | 5.51 |
Ddx6 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 | 1.53 | 4.87 |
Klk1 | kallikrein 1 | 1.65 | 4.86 |
Ugcg | UDP-glucose ceramide glucosyltransferase | 1.50 | 4.68 |
Hspa4l | heat shock protein a4-like | 1.60 | 4.56 |
Cd209d | CD209d antigen | 1.59 | 4.46 |
Strn3 | striatin, calmodulin binding protein 3 (probed in intron) | 1.57 | 4.37 |
A230046K03Rik | RIKEN cDNA A230046K03 gene | 1.55 | 4.23 |
Lifr | leukemia inhibitory factor receptor | 1.55 | 4.21 |
Slc5a3 | solute carrier family 5 (inositol transporters), member 3 | 1.54 | 4.18 |
Hspa1a | heat shock protein 1A | 1.70 | 4.11 |
2810442I21Rik | RIKEN cDNA 2810442I21 gene | 1.69 | 4.07 |
Tbc1d8 | TBC1 domain family, member 8 | 1.52 | 4.06 |
Rbm25 | RNA binding motif protein 25 | 1.55 | 3.40 |
Down-regulated in ΔmU50(HG-b) mice | |||
Gm13051 | Zinc finger-containing | 0.49 | −6.68 |
Fscn1 | fascin homolog 1, actin bundling protein | 0.49 | −5.73 |
Sdc1 | syndecan 1 | 0.59 | −4.89 |
Chst1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 0.60 | −4.81 |
Ly6k | lymphocyte antigen 6 complex, locus K | 0.62 | −4.52 |
Idi1 | isopentenyl-diphosphate delta isomerase | 0.62 | −4.52 |
Lman1 | lectin, mannose-binding, 1 | 0.62 | −4.47 |
also known as Col6a4 (collagen, type VI, alpha 4).
Genes that exhibit >1.5-fold up/down-regulation between wild-type and ΔmU50(HG-b) mice are listed. Probes target to immunoglobulin genes are omitted from the list (see Materials and Methods; complete dataset is available on online GEO database under the accession number GSE41164).