. Author manuscript; available in PMC: 2014 Jan 14.

Published in final edited form as: Cell Physiol Biochem. 2013 Jan 14;31(1):44–55. doi: 10.1159/000343348

Table 1.

Effect of 3h isoprenaline infusion on renal function in CD38^+/+and CD38^−/− mice.

		Basal	Iso 1h	Iso 2h	Iso 3h

GFR (ml/min/gkw)	CD38^+/+	0.92±0.09	0.58±0.11	0.77±0.13	0.74±0.13
GFR (ml/min/gkw)	CD38^−/−	0.95± 0.15	0.37±0.09	0.62±0.15	0.62±0.13
UV (μl/min/gkw)	CD38^+/+	52.23±6.21	29.22±8.02	25.32±7.82	25.81±4.47
UV (μl/min/gkw)	CD38^−/−	36.33±3.50^*	8.46±2.40^*	6.43±0.93^*	7.48±1.19^*
UNaV (μmol/min/gkw)	CD38^+/+	13.06±1.93	5.95±1.74	4.71±2.38	3.10±1.38
UNaV (μmol/min/gkw)	CD38^−/−	6.99±0.84^*	2.08±0.53^*	0.76±0.11	1.14±0.25
FENa (%)	CD38^+/+	4.90± 0.31	1.62±0.31	1.26±0.32	1.32±0.45
FENa (%)	CD38^−/−	3.21± 0.21^*	1.13±0.35	1.31±0.80	1.65±0.97
UkV (μmol/min/gkw)	CD38^+/+	3.55± 1.01	1.94±0.41	1.53±0.52	1.95±0.42
UkV (μmol/min/gkw)	CD38^−/−	2.22± 0.42	0.99±0.36	1.35±0.25	1.85±0.66
FEk (%)	CD38^+/+	0.43± 0.06	0.24±0.04	0.21±0.06	0.25±0.05
FEk (%)	CD38^−/−	0.29± 0.03	0.21±0.03	0.23±0.05	0.26±0.06

Iso: Isoprenaline, h: hour, GFR: glomerular filtration rate, UV: urine volume, U_NaV: urinary sodium excretion, U_kV: urinary potassium excretion, FE_NaV: fractional excretion of sodium, FE_kV: fractional excretion of potassium,

p<0.05 vs. CD38^+/+ mice.