. Author manuscript; available in PMC: 2014 Jan 14.

Published in final edited form as: Cell Physiol Biochem. 2013 Jan 14;31(1):44–55. doi: 10.1159/000343348

Table 2.

Effect of 3h RPP reduction on renal function in CD38^+/+and CD38^−/− mice.

		Basal	Low RPP 1h	Low RPP 2h	Low RPP 3h

GFR (ml/min/gkw)	CD38^+/+	1.04± 0.06	0.81±0.20	0.83±0.27	0.85±0.25
GFR (ml/min/gkw)	CD38^−/−	0.96± 0.04	0.34±0.14	0.76±0.14	0.76±0.16
UV (μl/min/gkw)	CD38^+/+	70.04± 6.47	18.01±3.01	16.70±3.45	21.93±3.82
UV (μl/min/gkw)	CD38^−/−	42.90± 5.58^*	4.87±0.73^*	4.52±0.73^*	5.88±1.86^*
UNaV (μmol/min/gkw)	CD38^+/+	9.19± 1.73	2.36±0.66	1.91±0.63	2.95±1.17
UNaV (μmol/min/gkw)	CD38^−/−	4.46± 0.66^*	0.55±0.12^*	0.54±0.16	0.54±0.19
FENa (%)	CD38^+/+	3.73± 0.48	1.04±0.13	0.87±0.13	1.34±0.48
FENa (%)	CD38^−/−	2.22± 0.38^*	0.50±0.11^*	0.35±0.10^*	0.29±0.09^*
UkV (μmol/min/gkw)	CD38^+/+	4.00± 0.44	1.60±0.30	1.39±0.23	1.93±0.49
UkV (μmol/min/gkw)	CD38^−/−	2.13± 0.31^*	0.94±0.39	1.16±0.32	1.44±0.32
FEk (%)	CD38^+/+	0.37± 0.05	0.20±0.03	0.19±0.03	0.26±0.09
FEk (%)	CD38^−/−	0.28± 0.05	0.16±0.03	0.17±0.03	0.22±0.03

RPP: renal renal perfusion, h: hour; GFR: glomerular filtration rate, UV: urine volume and U_NaV: urinary sodium excretion, U_kV: urinary potassium excretion, FE_NaV: fractional excretion of sodium, FE_kV: fractional excretion of potassium,

p<0.05 vs. CD38^+/+ mice.