Table 3.

Summary of supporting evidence for allergy loci.

SNP	region	repla	atopyb	autoc	nsSNPd	eQTLe	gene contextf
rs2101521	4p14	***			*	TLR6	TLR1-[]--TLR6
rs1438673	5q22.1	***	**				WDR36-[]--CAMK4
rs2155219	11q13.5	***	***	**			C11orf30--[]--LRRC32
rs10189629	2q12.1	**	*				IL1RL2--[]--IL1RL1
rs6906021	6p21.32	***					HLA-DQA1--[]-HLA-DQB1
rs9266772	6p21.33	**					HLA-C[]--MICA
rs7720838	5p13.1	*		*			[]PTGER4
rs2117339	2q33.1			*		PLCL1	[PLCL1]
rs9860547	3q28	***		***		BCL6	[LPP]
rs7032572	9p24.1		**				RANBP6[]--IL33
rs6021270	20q13.2						[NFATC2]
rs9303280	17q12		***	***	*	IKZF3	[GSDMB]
rs17293632	15q22.33			*			[SMAD3]
rs962993	10p14	*					GATA3[]
rs17388568	4q27	***	*	***			[ADAD1]
rs9671863	14q21.1						FOXA1--[]TTC6
rs2202749	8q21.13	***					TPD52[]ZBTB10
rs13416555	2p25.1	***				ID2	[]ID2
rs7203459	16p13.13		*	*			[CLEC16A]
rs2107357	16p12.1						IL4R--[]--IL21R
rs2056417	1p36.22					PEX14	[PEX14]
rs970924	11q24.3						[]ETS1

^aStrength of replication for allergic sensitization²⁰:

^*P<0.05,

^**P<0.005,

^***P<0.0005 (Supplementary Table 4).

^bNearby (<500kb, r²>0.5) GWAS findings for atopy phenotypes (Supplementary Table 7).

^cNearby (<500kb, r²>0.5) GWAS findings for autoimmune disease phenotypes (Supplementary Table 7).

^dnsSNP: * r²>0.5 with nonsynonymous SNP (Supplementary Table 8).

^eAssociation with expression of gene listed (Supplementary Table 9).

^fAs defined in Table 2.