Table 3.
The genotype and allele frequencies of XRCC1 gene polymorphisms in cases and controls
| Groups | c.910A>G | c.1804C>A | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genotype frequencies (%) | Allele frequencies (%) | Genotype frequencies (%) | Allele frequencies (%) | |||||||||||
| AA | AG | GG | A | G | χ2 | P | CC | CA | AA | C | A | χ2 | P | |
| Cases (n = 395) | 180(45.57) | 169(42.78) | 46(11.65) | 529(66.96) | 261(33.04) | 0.4307 | 0.8063 | 210(53.17) | 146(36.96) | 39(9.87) | 566(71.65) | 224(28.35) | 3.2183 | 0.2001 |
| Controls (n = 398) | 227(57.03) | 142(35.68) | 29(7.29) | 596(74.87) | 200(25.13) | 1.0657 | 0.5869 | 231(58.04) | 151(37.94) | 16(4.02) | 613(77.01) | 183(22.99) | 2.0327 | 0.3619 |
| Total (n = 793) | 407(51.32) | 311(39.22) | 75(9.46) | 1125(70.93) | 461(29.07) | 1.8990 | 0.3869 | 441(55.61) | 297(37.45) | 55(6.94) | 1179(74.34) | 407(25.66) | 0.26737 | 0.8749 |
| χ2 = 11.6137, P = 0.0030 | χ2 = 12.0393, P = 0.0005 | χ2 = 10.6912, P = 0.0048 | χ2 = 5.9812, P = 0.0145 | |||||||||||