Table 4.
The association between gastric cancer risk and XRCC1 gene polymorphisms.
| SNPs | Comparisons | Test of association | ||
|---|---|---|---|---|
| OR (95% CI) | χ2-value | P-value | ||
| c.910A>G | Homozygote comparison (GG vs. AA) | 2.00(1.21-3.31) | 7.43 | 0.006 |
| Heterozygote comparison (AG vs. AA) | 1.50(1.12-2.02) | 7.21 | 0.007 | |
| Dominant model (GG/AG vs. AA) | 1.59(1.20-2.10) | 10.42 | 0.001 | |
| Recessive model (GG vs. AG/AA) | 1.68(1.03-2.73) | 4.39 | 0.036 | |
| Allele contrast (G vs. A) | 1.47(1.18-1.83) | 12.03 | 0.001 | |
| c.1804C>A | Homozygote comparison (AA vs. CC) | 2.68(1.46-4.94) | 10.59 | 0.001 |
| Heterozygote comparison (CA vs. CC) | 1.06(0.79-1.43) | 0.17 | 0.682 | |
| Dominant model (AA/CA vs. CC) | 1.22(0.92-1.61) | 1.91 | 0.167 | |
| Recessive model (AA vs. CA/CC) | 2.62(1.44-4.76) | 10.51 | 0.001 | |
| Allele contrast (A vs. C) | 1.33(1.06-1.66) | 5.98 | 0.014 | |
SNPs, single nucleotide polymorphisms; OR, odds ratio; CI, confidence interval; vs., versus.