Table 3.

Distribution of clustering patterns for 12 comorbidities by disease category and rate ratios for in-hospital death among adult hospitalizations with a diagnosis of VTE, NIS, 2009

Total # of categories	Cancera	Cardiovascular /Blood/Respiratoryb	Gastrointestinal /Renalc	Nutritional /Bodyweightd	Unweighted n	Estimated distribution		In-hospital death
	Clustering pattern					N	%	aRRe	CI
4	+f	+	+	+	740	3,730	0.5	10.28	8.66-12.20
3	+	+	+	-g	667	3,380	0.4	6.38	4.97-8.19
3	-	+	+	+	6,441	32,299	4.2	7.85	7.00-8.79
3	+	-	+	+	453	2,282	0.3	6.86	5.40-8.72
3	+	+	-	+	3,795	19,138	2.5	8.45	7.51-9.50
2	+	+	-	-	5,201	26,313	3.4	5.00	4.42-5.67
2	-	+	+	-	7,344	37,045	4.8	3.73	3.29-4.24
2	-	-	+	+	3,707	18,677	2.4	4.41	3.81-5.11
2	+	-	+	-	652	3,302	0.4	3.12	2.23-4.38
2	+	-	-	+	3,091	15,626	2.0	5.44	4.71-6.27
2	-	+	-	+	17,815	89,284	11.5	6.10	5.48-6.80
1	+	-	-	-	6,203	31,452	4.1	2.46	2.11-2.86
1	-	+	-	-	33,267	168,271	21.8	2.74	2.48-3.03
1	-	-	+	-	6,032	30,422	3.9	1.65	1.35-2.01
1	-	-	-	+	13,715	68,954	8.9	2.98	2.66-3.34
0	-	-	-	-	44,001	223,098	28.9	1.00	Referenceh
Total number of hospitalizations					153,124	773,273	100.0	-	-

a. Presence of one or more comorbidities of lymphoma, metastatic cancer, and solid tumor without metastasis. b. Presence of one or more comorbidities of congestive heart failure, chronic pulmonary disease, coagulopathy, peripheral vascular disorders, and pulmonary circulation disorders. c. Presence of one or more comorbidities of liver disease and renal failure. d. Presence of one or more comorbidities of fluid and electrolyte disorders and weight loss. e. Rate ratios from log-linear regression model that adjusted for age, sex, race/ethnicity, days of hospital stay, primary expected payer, major operating room procedure, and comorbidities retained without 12 comorbidities. f. Presence of one or more comorbidities of the disease category. g. Absence of any comorbidity of the disease category. h. Absence of 12 comorbidities.