Figure 3.

Genes Regulated by E₂ in Vivo Are Bound by Cyclin D1 by ChIP-Seq. A, Comparison of genes occupied by cyclin D1 in ChIP-Seq to those regulated by E₂ in cyclin D1^+/+ mouse mammary gland and (B) those E₂-responsive genes that are regulated in a cyclin D1-dependant manner. C, Location of and (D) representative tag density profiles for, cyclin D1-occupied genes that are regulated by E₂. Vertical axis shows average peak height and horizontal axis depicts chromosomal location of cyclin D1-associated interval sequence. TSS, transcription start site.