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. 2013 Aug 22;3(8):e003259. doi: 10.1136/bmjopen-2013-003259

Table 4.

Studies by age group, directionality and quality grading

Age group Direction of findings Number of studies (%) Quality grading (%)
Infancy ≤1 year of age n=18 No association between IQ and BF 9 (50) A—3 (33.3)
B—3 (33.3)
C—3 (33.3)
Positive association between IQ and BF 5 (28) A—0 (0)
B—1 (20)
C—4 (80)
Initial positive association which became negative after adjustment for confounders. 2 (11) A—0 (0)
B—1 (50)
C—1 (50)
Initial positive association weakened after adjustment for confounders but remained statistically significant 2 (11) A—1 (50)
B—0 (0)
C—1 (50)
Childhood 1–18 years of age n=70 No association between IQ and BF 14 (20) A—3 (21)
B—5 (36)
C—6 (43)
Positive association between IQ and BF 26 (37) A—10 (38.5)
B—6 (23)
C—10 (38.5)
Initial positive association which became negative after adjustment for confounders. 16 (23) A—6 (37.5)
B—6 (37.5)
C—4 (25)
Initial positive association weakened after adjustment for confounders but remained statistically significant 14 (20) A—12 (86)
B—2 (14)
C—0 (0)
Adulthood ≥18 years of age n=5 No association between IQ and BF 2 (40) A—0 (0)
B—1 (50)
C—1 (50)
Positive association between IQ and BF 1 (20) A—0 (0)
B—1 (100)
C—0 (0)
Initial positive association which became negative after adjustment for confounders. 1 (20) A—0 (0)
B—1 (100)
C—0 (0)
Initial positive association weakened after adjustment for confounders but remained statistically significant 1 (20) A—1 (100)
B—0 (0)
C—0 (0)

Infancy: Refs. 22 24 35–37* 38 51 54 60 64* 69 70* 72* 73 74* 78* 86* 90*

Adulthood: Refs. 39 43* 44 71 83

*Study examined two different age groups and therefore included in several categories.

BF, breastfeeding.