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. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Stroke. 2013 Mar 26;44(5):1282–1287. doi: 10.1161/STROKEAHA.111.000529

Table 4.

Hazard ratio, 95% confidence limits and p-value for predictors of ICH, shown in univariate, and after adjustment in incremental regression models; and final estimates from the most parsimonious model (also adjusted for age, race and age-race interaction)

Univariate
effects		 Adjustment
for age-race		 Further
adjustment for
sex		 Further
adjustment for
SBP		 Further
adjustment for
warfarin use		 Most
parsimonious
model
Age (10 year) Because of age-race interactions, estimates in these models is provided in Table 3
Black Race
Male Sex 2.83
(1.63 – 4.91)
0.0003		 2.75
(1.60 – 4.73)
0.0003		 2.60
(1.50 – 4.48)
0.0007
Region Belt 0.71
(0.41 – 1.23)
0.22		 0.74
(0.43 – 1.27)
0.28		 0.76
(0.44 – 1.32)
0.33		 0.75
(0.43 – 1.30)
0.31		 0.76
(0.44 – 1.31)
0.32
Buckle 0.90
(0.47 – 1.70)
0.74		 0.94
(0.49 – 1.78)
0.84		 1.01
(0.53 – 1.93)
0.77		 1.01
(0.53 – 1.94)
0.97		 1.01
(0.53 – 1.93)
0.97
Hypertension 1.57
(0.91 – 2.68)
0.10		 1.35
(0.78 – 2.34)
0.28		 1.38
(0.80 – 2.38)
0.25		 1.08
(0.59 – 1.98)
0.78		 1.06
(0.58 – 1.94)
0.85
SBP (10 mmHg) 1.24
(1.10 – 1.40)
0.0003		 1.20
(1.06 – 1.36)
0.0053		 1.18
(1.04 – 1.35)
0.011		 1.19
(1.04 – 1.36)
0.0089
Diabetes 1.28
(0.70 – 2.33)
0.43		 1.29
(0.71 – 2.33)
0.40		 1.23
(0.68 – 2.22)
0.50		 1.17
(0.64 – 2.12)
0.61		 1.14
(0.63 – 2.08)
0.66
CKD 2.26
(1.28 – 3.98)
0.0052		 1.75
(0.98 – 3.13)
0.058		 1.74
(0.97 – 3.10)
0.062		 1.59
(0.89 – 2.86)
0.12		 1.54
(0.85 – 2.77)
0.15
Total Chol (10 mg/dL) 0.95
(0.89 – 1.01)
0.12		 0.96
(0.90 – 1.03)
0.28		 0.99
(0.93 – 1.06)
0.82		 0.99
(0.92 – 1.05)
0.70		 0.99
(0.93 – 1.06)
0.75
LN(Trig) 0.82
(0.49 – 1.38)
0.45		 0.84
(0.49 – 1.44)
0.52		 0.84
(0.50 – 1.43)
0.53		 0.80
(0.47 – 1.36)
0.41		 0.79
(0.46 – 1.34)
0.38
HDL (10 mg/dL) 0.87
(0.75 – 1.02)
0.098		 0.87
(0.74 – 1.02)
0.090		 0.97
(0.82 – 1.15)
0.76		 0.98
(0.83 – 1.15)
0.78		 0.98
(0.83 – 1.16)
0.84
LDL (10 mg/dL) 0.97
(0.91 – 1.05)
0.49		 0.99
(0.92 – 1.07)
0.83		 1.00
(0.93 – 1.08)
0.90		 1.00
(0.93 – 1.08)
1.00		 1.00
(0.93 – 1.08)
0.94
LN(CRP) 1.06
(0.84 – 1.32)
0.63		 1.06
(0.84 – 1.33)
0.60		 1.14
(0.90 – 1.43)
0.28		 1.12
(0.89 – 1.41)
0.34		 1.10
(0.87 – 1.39)
0.43
Smoking
(vs. never-smoking)		 Past 1.31
(0.77 – 2.21)
0.32		 1.27
(0.75 – 2.15)
0.37		 1.04
(0.60 – 1.78)
0.89		 1.02
(0.60 – 1.75)
0.94		 1.02
(0.60 – 1.76)
0.93
Current 1.22
(0.56 – 2.66)
0.61		 1.53
(0.69 – 3.40)
0.29		 1.38
(0.62 – 3.08)
0.43		 1.32
(0.59 – 2.95)
0.50		 1.33
(0.59 – 2.99)
0.48
Smoking (versus non-smoking) 1.07
(0.51 – 2.25)
0.86		 1.36
(0.63 – 2.92)
0.43		 1.35
(0.63 – 2.91)
0.44		 1.30
(0.60 – 2.82)
0.50		 1.32
(0.61 – 2.85)
0.48
Alcohol Use 1.05
(0.64 – 1.75)
0.84		 1.16
(0.71 – 1.90)
0.55		 0.97
(0.59 – 1.61)
0.91		 0.97
(0.58 – 1.60)
0.89		 0.97
(0.58 – 1.60)
0.90
Warfarin use 3.54
(1.63 – 7.67)
0.0014		 2.40
(1.08 – 5.33)
0.032		 2.15
(0.96 – 4.78)
0.062		 2.24
(1.01 – 5.00)
0.048		 2.24
(1.01 – 5.00)
0.048
Aspirin Use 1.51
(0.87 – 2.59)
0.14		 1.32
(0.76 – 2.32)
0.32		 1.19
(0.67 – 2.11)
0.55		 1.19
(0.67 – 2.10)
0.55		 1.27
(0.71 – 2.26)
0.41
NSAID Use 0.50
(0.17 – 1.43)
0.19		 0.55
(0.19 – 1.58)
0.26		 0.63
(0.22 – 1.80)
0.38		 0.61
(0.21 – 1.77)
0.36		 0.62
(0.22 – 1.79)
0.38